治疗疼痛的手术前 gabapentin:一个随机的,安慰剂控制的临床试验,在接受内膜整形的患者中进行
Glaucio Boechat Costa1, Luana Assis Ferreira1, Marina Ayres Delgado2
1Programa de Pós Graduação em Ciências da Saúde, Faculdade de Saúde Santa Casa BH, Belo Horizonte, Minas Gerais, Brazil.
概括
在接受 inguinal hernioplasty 的患者中,手术前的 gabapentin 显著降低了术后疼痛和吗啡的使用. 这项研究强调了 gabapentin 的重要性.
科学领域:
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
背景情况:
- 加巴丁在外科手术期间用于治疗疼痛,结果各不相同.
- 临床实践,手术类型和时间在不同研究中有所不同.
研究的目的:
- 评估手术前的加巴丁是否能在 inguinal hernioplasty 后减少术后的疼痛.
- 评估 gabapentin 对这种患者群体疼痛和阿片类药物消费的影响.
主要方法:
- 一次双盲,随机,安慰剂对照试验.
- 77名患者接受了900毫克 gabapentin 或安慰剂.
- 疼痛 (视觉模拟尺度) 和吗啡消费是主要结局.
主要成果:
- gabapentin 组报告说术后疼痛显著降低 (P < .001).
- 在 gabapentin 组中,吗啡的使用明显减少 (5.3% vs 74.4%,P < .001).
- 两组之间没有发现不良事件的显著差异.
结论:
- 在外科手术期间, gabapentin 有效地减少了手术后的疼痛,在 inguinal hernioplasty 之后.
- gabapentin 显示出显著的阿片类药物节约作用.
- 这项研究表明, gabapentin 在治疗疼痛和减少手术后阿片类药物依赖方面具有长期的益处.
关键词:
inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty inguinal hernioplasty在外科手术期间服用 gabapentin.术后疼痛 术后疼痛 术后疼痛相关概念视频
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