相关实验视频

Updated: Aug 8, 2026

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
14:57

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

Published on: March 23, 2011

94.0K

HDAC6通过HSP90-HSF1通路调节APP/PS1转基因小鼠的认知行为功能和海马组织病理变化

Bingyi Wang1, Siyu Liu1, Kaimin Hao1

  • 1Department of Basic Medicine, Fenyang College of Shanxi Medical University, Fenyang, 032200, China.

Experimental brain research
|June 27, 2024
PubMed
概括

这项研究表明,抑制基因组脱乙酶6 (HDAC6) 能改善阿尔茨海默氏症患者的认知功能.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.热冲击因子 1 的热冲击因子 1 .组织脱酸酶 6,热冲击蛋白 90 90

更多相关视频

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging09:37

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging

Published on: July 14, 2016

8.3K
Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue09:43

Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue

Published on: November 30, 2018

21.3K

相关概念视频

Huntington Disease l: Introduction01:21

Huntington Disease l: Introduction

Huntington disease or HD is a progressive, fatal neurodegenerative disorder inherited in an autosomal dominant pattern.PathophysiologyIt is caused by expansion of the CAG trinucleotide repeat in the HTT gene on chromosome 4 (4p16.3), producing an abnormal huntingtin protein with an expanded polyglutamine tract. This misfolded protein disrupts cellular function, leading to neuronal death. Normal alleles have ≤26 repeats, 27–35 are intermediate (risk of expansion), 36–39 show reduced penetrance,...