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Updated: Jun 22, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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作为新型UPAR抑制剂的diltiazem的接口驱动结构演变:从in silico设计到体外评估

Song Xie1,2, Yang Zhou2, Hao Zhu1

  • 1School of Pharmacy, Nantong University, Nantong, 226001, Jiangsu, China.

Molecular diversity
|June 27, 2024
PubMed
概括

研究人员开发了针对尿激酶类型等离子素激活体受体 (uPAR) 的新型diltiazem衍生物,以抑制癌症转移. 这些新化合物显示出有前途的抗转移活性,验证了in silico药物设计策略.

关键词:
这是一种抗转移的药物.超动力学是什么?超动力学是什么?分子动力学模拟模型uPAR 抑制剂的使用

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