在黑人个体中,子宫内膜厚度作为子宫内膜癌的诊断分组
Kemi M Doll1, Mindy Pike1, Julianna Alson1
1Department of Obstetrics and Gynecology, Fred Hutchinson Cancer Center, University of Washington, Seattle.
JAMA oncology
|June 27, 2024
概括
对于具有子宫内膜癌 (EC) 风险因素的黑人个人来说,经阴道超声波选策略是不可靠的. 建议采取组织样本,特别是在绝经后出血时,以提高诊断准确度.
科学领域:
- 妇科 妇科医生 妇科
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 在诊断时的子宫内膜癌 (EC) 阶段存在种族差异.
- 通过阴道的超声波 (TVUS) 被用作分拣策略.
- 它的表现可能会导致黑人个体的差异.
研究的目的:
- 评估黑人EC诊断中子宫内膜厚度 (ET) 值的假负概率.
- 为了确定EC风险因素是否影响ET分拣性能.
主要方法:
- 使用电子健康记录和行政数据 (2014-2020) 进行回顾性诊断研究.
- 评估了经过子宫切除术的黑人个体.
- 分析了用于EC诊断准确性的TVUS子宫内膜厚度 (ET) 值.
主要成果:
- 5毫米的ET值在黑人个体中具有11.4%的EC错误阴性概率.
- 错误阴性率在EC风险组中相似,但在部分ET可见性或骨盆疼痛时更高.
- 在4mm和3mm的值下,假负的概率分别为9.5%和3.8%.
结论:
- 对于患有EC风险的黑人成年人来说,TVUS ET分拣策略是不可靠的.
- 强烈建议在绝经后出血的个体采取组织样本.
- 需要改进选策略,以解决EC诊断中的种族差异.
相关概念视频
Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
External Anatomy of the Kidney
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
Internal Anatomy of the Kidney
The kidneys are essential organs in the human body, performing a myriad of tasks that maintain homeostasis and overall health.
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...


