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Updated: Jun 22, 2025

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对于NACC2-NTRK2融合蛋白激活的关键领域

Wei Yang1, April N Meyer1, Zian Jiang1

  • 1Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America.

PloS one
|June 27, 2024
PubMed
概括

NACC2-NTRK2融合蛋白通过BTB域多元化激活NTRK2激酶活性来驱动儿科脑癌. 抑制这种BTB域可能提供一种新的癌症治疗策略.

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