在传染病中使用专家意见的临床指南-A元流行病学研究
Blin Nagavci1, Lukas Schwingshackl2, Ignacio Martin-Loeches3
1Doctoral School of Clinical Medicine, Semmelweis University, Budapest, Hungary.
PloS one
|June 27, 2024
概括
专家意见在近一半的国际传染病指南中使用,通常在证据分级系统中使用. 方法有所不同,这凸显了在制定指南时需要标准化的需要.
科学领域:
- 传染病流行病学 传染病流行病学
- 临床指南开发 临床指南开发
- 基于证据的医学基于证据的医学.
背景情况:
- 专家意见经常被纳入临床实践指南.
- 然而,它在国际传染病指南中的具体用途仍未得到审查.
- 本研究通过绘制专家意见的流行程度和方法集成来解决这一差距.
研究的目的:
- 在国际传染病指南中绘制专家意见的流行程度和使用情况.
- 分析有关专家意见的本指南的方法方面.
- 识别专家意见的应用和报告中的变化.
主要方法:
- 使用PubMed和Trip医疗数据库的系统搜索进行了一项超流行病学研究.
- 包括2018年1月至2023年5月间发布的国际传染病指南.
- 关于指南特征,专家意见使用和方法论严谨性的数据被提取并描述性和比较性地分析.
主要成果:
- 在分析的66条指南中,48.5%包含专家意见,通常属于证据层次结构.
- 使用专家意见的指导方针发布了更多的建议 (48.82 vs 19.13),但报告的查流程图较少 (25% vs 65%) 和偏差风险评估 (19% vs 78%) 与没有使用专家意见的指导方针相比.
- 在带有专家意见和没有专家意见的指南之间观察到显著的方法差异.
结论:
- 专家意见是国际传染病指南近一半的共同组成部分.
- 在使用专家意见的方法,形式和术语方面存在相当大的差异.
- 需要进行标准化和进一步的研究,以提高传染病指南的质量和一致性.
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