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I型常规树突细胞促进胰腺癌的免疫治疗

Krishnan K Mahadevan1, Allison M Dyevoich2, Yang Chen1

  • 1Department of Cancer Biology, Metastasis Research Center, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Science (New York, N.Y.)
|June 27, 2024
PubMed
概括

与胰腺癌并发的胰腺炎 (PDAC) 激活特定的免疫细胞 (cDC1). 结合cDC1疫苗和免疫检查点阻断疗法 (iCBT) 有效治疗PDAC并增强抗瘤免疫力.

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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