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Updated: Jun 22, 2025

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
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Published on: December 1, 2020

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通过扰乱生物网络响应功能来优先考虑药物目标

Matthew C Perrone1, Michael G Lerner2, Matthew Dunworth3

  • 1Institute for Computational Medicine and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America.

PLoS computational biology
|June 27, 2024
PubMed
概括

新的网络扰动理论,NetPert,确定了可以药物治疗的中间体,用于无法药物治疗的癌症标. 这种方法通过优先考虑治疗干预的关键信号蛋白来增强药物发现.

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