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Updated: Jun 22, 2025

High Sensitivity Measurement of Transcription Factor-DNA Binding Affinities by Competitive Titration Using Fluorescence Microscopy
06:38

High Sensitivity Measurement of Transcription Factor-DNA Binding Affinities by Competitive Titration Using Fluorescence Microscopy

Published on: February 7, 2019

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在转录调节剂中吸附黄类药物TtgR:相对结合的自由能量和分子间相互作用

Yuxuan Wu1, Shi Zhang1, Darrin M York1

  • 1Department of Chemistry and Chemical Biology, Institute for Quantitative Biomedicine, Laboratory for Biomolecular Simulation Research, Rutgers University, Piscataway, New Jersey 08854, United States.

The journal of physical chemistry. B
|June 27, 2024
PubMed
概括

伪白虫DOT-T1E使用TtgABC排泄进行阻力. 这项研究揭示了黄胺如何与TtgR调节器结合,揭示了驱动抗菌素耐药性的关键分子相互作用.

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