在健康的孕妇中使用心率变量进行自主神经系统评估:系统性审查
Zahra Sharifiheris1, Amir Rahmani1, Joseph Onwuka1
1University of California, Irvine, Irvine, CA, United States.
JMIR bioinformatics and biotechnology
|June 27, 2024
概括
这次审查发现,虽然心率变化 (HRV) 可以测量怀孕期间自主神经系统 (ANS) 功能,但不一致的方法阻止了对正常ANS模式的可靠识别. 需要更多的研究来标准化对孕妇的HRV评估.
科学领域:
- 身体生理学 身体生理学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 生物医学工程 生物医学工程
背景情况:
- 自主神经系统 (ANS) 对妊娠适应至关重要,失调与不利的孕产妇和新生儿结局有关.
- 了解怀孕期间母亲的ANS功能对于识别潜在并发症至关重要.
研究的目的:
- 系统地审查使用心率变化 (HRV) 来评估健康孕妇ANS功能的研究.
- 为了确定是否已经确定了特定的HRV模式,表明在怀孕期间ANS的正常功能.
主要方法:
- 由PRISMA指导的系统审查,搜索CINAHL,PubMed,SCOPUS和Web of Science没有时间限制.
- 包括在健康孕妇中评估HRV的研究,使用NHLBI工具进行质量评估.
- 由于研究范围,方法和变量的异质性,用于数据提取的叙事综合.
主要成果:
- 八项研究符合纳入标准,主要使用心电图来测量HRV.
- 确定了三个HRV运行方法:线性频率域 (FD),线性时间域 (TD) 和非线性.
- TD和大多数FD指数从第一季度到第三季度下降;LF[nu]和LF/HF比率增加,表明同情活动上升.
结论:
- 确定了HRV方法和潜在模式,但测量工具,时间框架和操作化方法的显著异质性限制了概括性和可靠性.
- 缺乏标准化的方法阻碍了在怀孕期间对正常ANS功能的HRV模式的明确识别.
- 需要进行进一步的研究,以确定在健康孕妇中可靠确定HRV模式的标准和方法.
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