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Updated: Jun 22, 2025

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长非编码RNA在小鼠核细胞中的差异表达在短毛RNA介导的dysferlin沉默后In Vitro:微阵列分析

Richa Singhal1, Rachel Lukose2, Gwenyth Carr3

  • 1Department of Biochemistry and Molecular Genetics, KY IDeA Networks of Biomedical Research Excellence Bioinformatics Core, University of Louisville, Louisville, KY, United States.

JMIR bioinformatics and biotechnology
|June 27, 2024
PubMed
概括

淋巴结节症与长非编码RNAs (lncRNAs) 和信使RNAs (mRNAs) 的改变表达有关. 这项研究确定了成千上万的差异表达的lncRNA和mRNA,这表明肌肉在疾病中的特定作用.

关键词:
在LGMD-2B中.不正常的表达方式.生物信息学是一种生物信息学.这种疾病被称为dysferlinopathy.基因本体学 基因本体学肢体-腰带肌肉缩症 2B 2B在ncRNA中,我们可以长非编码RNAs的编码.它们是mRNARNA.传递 RNA 的信使 RNA.肌肉发育不良 肌肉发育不良 肌肉发育不良没有编码的RNA.蛋白质表达 蛋白质表达qRT-PCR 是一个很好的方法.实时聚合酶连锁反应的定量实时聚合酶连锁反应转录 转录 是一种转录.

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