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Updated: Jun 22, 2025

Real-time Analysis of Gut-brain Neural Communication: Cortex wide Calcium Dynamics in Response to Intestinal Glucose Stimulation
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通过共价捕获延长GLP-1受体的激活

Özge Ünsal1, Z Selin Bacaksiz1, Vladislav Khamraev1

  • 1Department of Chemistry, Tufts University, Medford, Massachusetts 02155, United States.

ACS chemical biology
|June 27, 2024
PubMed
概括

研究人员设计了一种新型的葡萄糖类-1 (GLP-1) 模拟物,该模拟物与GLP-1受体 (GLP-1R) 共同结合. 这种修改显著延长受体激活,为开发更有效的代谢性疾病治疗提供了有希望的策略.

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