相关实验视频

Updated: Jul 19, 2026

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes

Published on: February 19, 2016

对具有高封装效率的尼纳米脂质体的潜在稳定剂的选,特征和机制

Qibin Li¹, Linao Lv¹, Weiqi Liang¹

¹College of Food Science and Technology, Guangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, Guangdong Provincial Engineering Technology Research Center of Marine Food, Key Laboratory of Advanced Processing of Aquatic Products of Guangdong Higher Education Institution, Guangdong Ocean University, Zhanjiang 524088, China.

|June 27, 2024

概括

库尔库纳米脂质体 (Cu-NLs) 实现了尼95.94%的封装效率,证明了增强细菌素输送和食品应用中的稳定性的新策略.

科学领域:

食品科学与技术食品科学与技术
纳米技术纳米技术
生物化学生物化学

背景情况:

尼辛封装效率 (EE%) 对于将生物活性成分装入纳米脂质体至关重要.
纳米脂质体稳定剂是改善EE%的关键,用于增强的输送系统.
多被探索为纳米脂质体的潜在稳定剂.

研究的目的:

选多作为高尼EE%的纳米脂质体的稳定剂.
为了表征素纳米脂质体 (Cu-NLs) 的统一性,稳定性和尼相互作用.
评估Cu-NLs对全脂牛奶中尼辛活性的保护作用.

主要方法:

三种多作为纳米脂质体稳定剂的选.
使用粒子大小,PDI,泽塔潜力,TEM,DSC和FT-IR,对Cu-NLs进行表征.
分子对接模拟以调查黄素-尼辛相互作用.
使用Cu-NLs对全脂牛奶中尼活性的评估.

主要成果:

库尔库纳米脂质体 (Cu-NLs) 获得了最高的NIsin EE% (95.94%).
-NLs表现出良好的均性和稳定性,尼在脂层边缘积累.
证实了黄素在脂层形成和结构改变中的参与.
在黄素和尼之间确定了气结合和水性相互作用.
Cu-NLs有效地保护了全脂牛奶中的尼活性.

结论:

黄素是一种有效的稳定剂,可以在纳米脂质体中增强尼辛EE%.
-NLs为稳定和释放尼和其他细菌素提供了一个有希望的战略.
这种方法改善了纳米脂质体在生物活性成分封装中的性能.

关键词:

库尔库明是一种黄素.封装效率封装效率是指封装效率是指封装效率.纳米脂质体中的纳米脂质体尼辛尼斯尼辛尼斯尼辛尼斯尼辛尼斯稳定剂是一种稳定剂.

更多相关视频

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids

Published on: May 4, 2018

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins

Published on: August 31, 2019

相关概念视频

Bioavailability Enhancement: Drug Stability Enhancement and GI Retention

Bioavailability Enhancement: Drug Stability Enhancement and GI Retention

Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...