在重症监护室中SARS-Cov2传播的途径:一个多中心前性研究
Yacine Tandjaoui-Lambiotte1, Alexandre Elabbadi2, Boubaya Marouane3
1Delafontaine Hospital, Department of Pulmonology and Infectious Diseases, Saint Denis, France; INSERM UMR 1272 Hypoxia & Lung, Bobigny, France; INSERM UMR 1137 IAME, Paris, France.
Journal of infection and public health
|June 27, 2024
概括
在ICU中,SARS-CoV-2的传播主要是通过受污染的表面 (fomites),而不是通过空气传播的途径. 患者的腹与表面污染的增加有关,这凸显了卫生保健工作者接触预防措施的重要性.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 环境健康 环境健康
背景情况:
- 了解重症监护室 (ICU) 中的SARS-CoV-2传播途径对于医疗保健工作者 (HCW) 的安全至关重要.
- 在ICU中SARS-CoV-2的空气传播和传播仍然是不确定的领域.
- 这项研究旨在评估空气和表面污染率,并确定患有SARS-CoV-2肺炎的ICU患者的相关风险因素.
研究的目的:
- 评估SARS-CoV-2污染在空气和ICU内的表面的流行程度.
- 识别导致SARS-CoV-2环境污染的风险因素.
- 为严重病情的COVID-19患者提供感染控制策略的信息.
主要方法:
- 一项前性,多中心,非干预性研究在法国三个ICU中进行.
- 在阳性PCR结果的48小时内收集了空气样本,表面抹布和医疗保健工作者面罩样本.
- 用滴滴数字PCR (ddPCR) 和定量PCR (qPCR) 来检测病毒.
主要成果:
- 在3.6%的患者的空气样本和53.3%的表面上检测到SARS-CoV-2.
- 卫生保健工作者面罩在4.4%的病例中呈阳性.
- 呼吸道样本中的更高的病毒载荷和腹的存在与表面污染的增加显著相关.
结论:
- 通过菌的接触途径似乎是SARS-CoV-2在这种ICU人群中的主要传播途径.
- 在这个特定的患者群体中,空气传播的SARS-CoV-2的存在并不频繁.
- 腹是表面污染的潜在危险因素,强调需要严格的接触预防措施.
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