基于虚拟现实的沉浸式对象位置记忆任务揭示了长期COVID中的空间长期记忆变化.
Tania Llana1, Sara Garces-Arilla2, M-Carmen Juan3
1Neuroscience Institute of Principado de Asturias (INEUROPA), Faculty of Psychology, Plaza Feijoo s/n, Oviedo, Asturias 33003, Spain; Department of Psychology, University of Oviedo, Faculty of Psychology, Plaza Feijoo s/n, Oviedo, Asturias 33003, Spain.
Behavioural brain research
|June 27, 2024
概括
与健康对照组相比,长期COVID患者表现出显著的物体定位记忆 (OLM) 缺陷,特别是延迟回忆. 沉浸式虚拟现实 (iVR) 任务有效地揭示了这些空间记忆障碍.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 传染病研究 传染病研究
背景情况:
- 长期COVID与神经和认知障碍有关,包括记忆功能障碍.
- 在长期COVID患者中观察到中间叶功能障碍,影响申报性记忆.
- 对象位置记忆 (OLM) 涉及将对象与它们的空间位置关联起来.
研究的目的:
- 用沉浸式虚拟现实 (iVR) 任务评估长期COVID患者的OLM缺陷.
- 为了比较长期COVID患者和健康对照者之间的OLM表现.
- 探索OLM,一般认知功能 (MoCA) 和语言/视觉空间跨度 (VSTM/SSTM) 之间的相关性.
主要方法:
- 对66名长期COVID患者和21名健康对照进行了基于iVR的OLM任务.
- 参与者的绩效指标包括正确的反应,任务尝试和时间投资.
- 用蒙特利尔认知评估 (MoCA),口头跨度 (VSTM) 和视觉空间跨度 (SSTM) 来评估认知功能.
主要成果:
- 长期COVID患者表现出较差的OLM,做更多的尝试,比对照群更长时间.
- 延迟的记忆回忆在长期COVID组中比立即回忆更受损.
- 在长期COVID患者中,较高的MoCA分数与更快的立即回忆相关;感染后的时间与回忆准确性有轻微的关联.
结论:
- 基于iVR的OLM任务在长期COVID中有效识别了空间和长期记忆的改变.
- 研究结果证实了长期COVID患者的记忆缺陷,突出显示了IVR在神经心理学研究中的实用性.
- iVR空间任务为理解和诊断后病毒综合征的认知障碍提供了一个有希望的途径.
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