Leonardo L Seidl1, Regina Moog2, Kirsten A Graeser2

  • 1Roche Pharma Research and Early Development, Therapeutic Modalities, pCMC, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070 Basel, Switzerland; Technical University of Munich, TUM School of Natural Sciences, Boltzmannstr. 10, 85748 Garching, Germany.

概括

锁定核酸 (LNA) 的雾化可以使用喷射和网状雾化器实现. 这项研究证实了LNA的稳定性,支持吸入作为这些生物治疗药物的潜在输送途径.