抑制UBA5通过阻断巨细胞M2两极化和抗西斯普拉丁耐药性来限制肺腺癌

Dacai Xu1, Donghui Zhang1, Wenlu Wei1

  • 1Zhanjiang Institute of Clinical Medicine, Central People's Hospital of Zhanjiang, Zhanjiang, 524033, PR China; Zhanjiang Central Hospital, Guangdong Medical University, Zhanjiang, 524033, PR China.

PubMed
概括

向UBA5,这是肺腺癌 (LUAD) 中的关键酶,抑制瘤生长和对西斯普拉丁的耐药性. UBA5的上调与不良的LUAD患者结果相关,并影响瘤免疫微环境.

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