与代谢功能障碍相关的稳态性肝病患者的身体组成:身体表面积的影响
Saori Onishi1, Akira Fukuda2, Masahiro Matsui1
1Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Osaka, Japan.
In vivo (Athens, Greece)
|June 27, 2024
概括
身体表面积 (BSA) 与代谢功能障碍相关的脂肪性肝病 (MASLD) 患者的脂肪和无脂肪质量有很强的相关性. 这表明BSA可以估计MASLD患者的身体组成.
科学领域:
- 代谢健康 代谢健康
- 肝脏疾病研究 肝脏疾病研究
- 身体组成分析分析.
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 影响着相当一部分人口.
- 了解身体成分对于管理MASLD至关重要.
- 以前的研究还没有充分探索MASLD患者的身体表面积 (BSA) 和身体组成之间的关系.
研究的目的:
- 调查身体表面积 (BSA) 和各种身体组成参数之间的关联.
- 为了确定BSA是否可以作为MASLD患者身体组成的预测标记.
主要方法:
- 对2141名被诊断患有MASLD的男性和986名被诊断患有MASLD的女性的身体组成数据进行了回顾性分析.
- 测量身体质量指数 (BMI),身体表面积 (BSA),脂肪质量和无脂肪质量.
- 在BSA和身体组成参数之间的统计相关性分析.
主要成果:
- 在MASLD患者中,BSA与脂肪质量 (男性:r=0.82;女性:r=0.87) 和无脂肪质量 (男性:r=0.95;女性:r=0.94) 都有显著的相关性.
- 这些相关性对两性都具有高度统计学意义 (p<0.0001).
- 男性和女性的BMI中位数相似,但BSA中位数和身体成分显著不同.
结论:
- 身体表面积 (BSA) 是MASLD患者身体组成的强有力的预测指标.
- BSA可以作为一个实用和可访问的临床标志物来估计身体成分.
- 进一步的研究可以探索BSA在MASLD管理中的临床实用性.
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