一个基于心电图的AI算法,用于早期检测肺高血压
Hilary M DuBrock1,2, Tyler E Wagner3,4,2, Katherine Carlson3,4
1Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA dubrock.hilary@mayo.edu.
The European respiratory journal
|June 27, 2024
概括
一个人工智能算法,PH早期检测算法 (PH-EDA),显示了使用心电图的早期肺高血压 (PH) 查的希望. 这种人工智能工具可以识别PH可能的患者,可能加速诊断和治疗.
科学领域:
- 心脏病学 心脏病学
- 人工智能的人工智能
- 医学诊断 医学诊断 医学诊断
背景情况:
- 肺高血压 (PH) 的早期诊断对于有效的管理至关重要.
- 肺高血压带来严重的健康风险,如果不及时发现.
研究的目的:
- 开发和验证用于PH查的AI算法,使用标准的12导心电图.
- 评估AI早期检测PH的能力,在临床诊断之前.
主要方法:
- 一个卷积神经网络,PH早期检测算法 (PH-EDA),被训练在回顾式心电图数据.
- 该算法根据心电图特征将患者分类为可能的PH或不可能的PH.
- 外部验证使用来自梅奥诊所和范德比尔特大学医学中心的独立数据集进行.
主要成果:
- PH-EDA实现了高性能,在诊断测试套件上Mayo Clinic的AUC为0.92,VUMC的AUC为0.88.
- 该算法在预防性查中表现出有效性,AUC分别为0.86和0.81.
- 在诊断前长达5年的时间里,显著的检测能力仍然存在,AUC仍然高于0.73.
结论:
- 通过使用心电图数据,PH-EDA可以有效地查肺高血压.
- 该算法显示了加速PH诊断和管理的潜力.
- 人工智能驱动的心电图分析为早期发现心血管疾病提供了有希望的途径.
相关概念视频
Pulse rhythm
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Electrocardiogram
An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and the T...
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and the T...


