青春期的认知功能和早期中风的风险
Aya Bardugo1,2,3,4, Cole D Bendor1,2,3,5, Carmit Libruder6
1Department of Military Medicine, Hebrew University, Jerusalem, Israel.
Journal of epidemiology and community health
|June 27, 2024
概括
青少年认知功能下降与早期中风风险显著增加有关. 即使考虑到肥胖和高血压等因素,这种关联仍然存在.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 在年轻人群中,中风发病率正在上升,风险因素不明.
- 青少年的认知功能被探索为早期中风的潜在预测因素.
研究的目的:
- 研究青春期认知功能与年轻时患中风风险之间的关联.
主要方法:
- 一项全国性的基于人口的队列研究,包括以色列超过170万名青少年 (16-20岁).
- 认知功能被评估并分为低,中或高.
- 数据与国家中风登记处联系在一起,使用Cox比例危险模型进行风险估计.
主要成果:
- 认知功能较低的人与认知功能较高的人相比,患早期中风的风险是2.68倍.
- 观察到一种剂量-反应关系,每单位的认知功能得分下降都与中风风险增加33%有关.
- 这些关联在调整身体质量指数,社会人口统计学,糖尿病和高血压后仍然显著,并且在40岁之前就很明显.
结论:
- 青少年较低的认知功能被确定为早期中风的潜在风险因素.
- 这一发现与肥胖和高血压一起,强调了认知健康在年轻人中风预防策略中的重要性.
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