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"慢性胰腺炎儿童的生活质量受损:一项多中心研究"
Ankit Agrawal1, Anshu Srivastava1, Prabhakar Mishra2
1Departments of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
概括
患有慢性胰腺炎 (CP) 的儿童的生活质量 (QOL) 显著降低,特别是在身体和心理社会方面. 疼痛和较低的社会经济地位 (SES) 是影响儿科 CP 患者 QOL 的关键因素.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 生活质量研究 研究 生命质量研究
- 儿童健康结果的结果
背景情况:
- 慢性胰腺炎 (CP) 对儿童生活质量 (QOL) 的影响尚未得到充分证实.
- 了解这些影响对于改善儿童CP患者的护理至关重要.
研究的目的:
- 评估印度CP儿童的QOL.
- 识别导致质量生活质量下降的因素.
- 为了确定这个人群中焦虑和抑郁症的患病率.
主要方法:
- 预计将在印度三个儿科胃肠病学中心招收121名患有CP的儿童 (8-18岁).
- 使用PedsQL 4.0尺度 (儿童和家长报告) 评估QOL.
- 使用RCADS 25尺度评估焦虑和抑郁;通过后勤回归分析贡献因素.
主要成果:
- 与健康对照组相比,患有CP的儿童的QOL显着较差 (74.6 ± 16对比87.5 ± 11.1,p < 0.0001).
- 疼痛和较低的社会经济地位 (SES) 与减少的身体和心理社会质量相关.
- 女孩报告心理社会质量比男孩差 (OR 3.1);焦虑和抑郁不常见 (1.6%).
结论:
- 患有CP的儿科患者体验到身体和心理社会质量质量受损.
- 疼痛和下SES是CP儿童QOL的显著不良决定因素.
- 在这个群体中,精神病并发症,如焦虑和抑郁,似乎并不常见.
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