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Updated: Jun 22, 2025

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跨物种的跨物种转录学揭示了由循环氨酸A重复给予诱导的保存性肝毒性途径

Nguyen Tran Nam Tien1, Trinh Tam Anh1, Nguyen Thi Hai Yen1

  • 1Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, Republic of Korea.

Toxicology mechanisms and methods
|June 27, 2024
PubMed
概括

环素A (CsA) 会导致肝脏的毒性. 这项研究跟踪了人类和动物模型中的基因表达变化,以揭示CsA.

关键词:
循环氨酸 (cyclosporine) 是一种氨酸.跨物种的交叉物种.有机生物有机物氧化应激是一种氧化应激.时间课程时间课程翻译毒理学 翻译毒理学

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Enterohepatic cycling involves the active secretion of drugs and their metabolites into the bile via transporters in the canalicular membrane of hepatocytes. This secretion is an integral part of the digestive process, releasing these substances into the gastrointestinal (GI) tract.
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