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口腔内镜肌切除术是一种有效的治疗 achalasia 结合间歇性
Peirong Xu1,2, Zuqiang Liu1,2, Jiyuan Zhang1,2
1Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Surgical endoscopy
|June 27, 2024
概括
口腔内镜肌切除术 (POEM) 是一种安全有效的治疗 achalasia,即使结合椎间. 这项研究发现,与没有间歇性的阿喀拉西亚患者相比,类似的成功率和不良事件.
科学领域:
- 胃肠病学和内镜检查
- 手术创新 在外科创新.
- 食道运动障碍 食道运动障碍
背景情况:
- 阿哈拉西亚是一种主要的食道运动障碍,其特征是受损的下食道关节放松和缺席的食道周围静止.
- 在患有秋症的患者中,椎是常见的,可能会使治疗复杂化.
- 口腔内镜肌切除术 (POEM) 已成为治疗阿喀拉西亚的最小侵入性治疗方法.
研究的目的:
- 评估POEM在同时患有椎的阿喀拉西亚患者的可行性和结果.
- 为了比较POEM的安全性和有效性,在患有阿喀拉西亚和椎间的患者和单独患有阿喀拉西亚的患者中.
主要方法:
- 从2016年1月到2022年12月,对2136名阿喀拉西亚患者的回顾性评估.
- 患有阿喀拉西亚和缺口的患者 (研究组) 与没有缺口的阿喀拉西亚患者 (对照组) 相匹配.
- 两组之间的手术前数据,手术不良事件和长期随访结果的比较.
主要成果:
- 在3.6%的阿喀拉西亚患者中存在沟;所有患者都成功接受了POEM.
- 研究和对照组显示的粘膜损伤,肺胸部,膜溢出和主要不良事件的发病率相似.
- 临床成功率,反流症状和质子抑制剂的使用在1,2年和3年随访的组之间是可比的.
结论:
- POEM是阿喀拉西亚患者的安全和有效的治疗选择,不管是否存在沟.
- 同时存在沟并不会对POEM结果产生负面影响.
- POEM 提供了一个可行的最小侵入性解决方案,用于涉及间歇性的复杂病例.
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