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Updated: Jun 26, 2026

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status
07:08

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status

Published on: October 20, 2016

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阿波利波蛋白E异型对人脑微血管内皮细胞中P-糖蛋白的丰度和功能的影响

Ethan Kreutzer1, Jennifer L Short2, Joseph A Nicolazzo3

  • 1Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria, 3052, Australia.

Pharmaceutical research
|June 27, 2024
PubMed
概括

阿波蛋白E (apoE) 异型不直接影响人脑内皮细胞中的P-糖蛋白 (P-gp) 丰度或功能. 这表明apoE可能不是阿尔茨海默病 (AD) 中改变的P-gp的原因.

关键词:
阿尔茨海默氏症 (AD) 是一种疾病.P-葡萄糖蛋白 (P-gp) 是一种蛋白质.阿波利波蛋白E (apoE) 是一种血脑屏障 (BBB) 是一个很大的障碍.

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