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Updated: Jun 22, 2025

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特定序列的动态DNA曲解释了线粒体TFAM在DNA包装和转录启动中的双重作用

Hyun Huh1, Jiayu Shen2,3, Yogeeshwar Ajjugal3

  • 1Institute for Quantitative Biomedicine, Rutgers University, Piscataway, NJ, 08854, USA.

Nature communications
|June 27, 2024
PubMed
概括

线粒体转录因子A (TFAM) 曲DNA以包装线粒体DNA (mtDNA) 并启动转录. 它的DNA曲动态依赖于序列,影响TFAM.

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