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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Serum Laboratory Studies, Stool Test, Breath Test01:30

Serum Laboratory Studies, Stool Test, Breath Test

Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
Urologic Endoscopic Procedure: Cystoscopic Examination01:28

Urologic Endoscopic Procedure: Cystoscopic Examination

Meaning of Cystoscopic Examination:Cystoscopy is an essential diagnostic tool in urology that is used to assess the structure and function of the genitourinary system. It provides a direct view of the urethra, bladder, and, in some cases, the ureteral openings. This procedure helps detect structural abnormalities, infections, cancers, and blockages in the urinary tract. There are two types of cystoscopy:Flexible cystoscopy is commonly performed in outpatient settings due to its less invasive...

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Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
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应该停止系统性前列腺活检吗?

Laurence Klotz1

  • 1University of Toronto, Sunnybrook Chair of Prostate Cancer Research, Sunnybrook Health Sciences Centre, 2075 Bayview Ave MG 408, Toronto, ON, M4N3M5, Canada. Laurence.Klotz@Sunnybrook.ca.

Prostate cancer and prostatic diseases
|June 27, 2024
PubMed
概括

系统活检可能会忽略显著的前列腺癌,但看不见的病变往往是惰的. 通过MRI和向活检进行监测是首选的,而不是系统活检,以获得更好的患者结果.

科学领域:

  • 泌尿器科 泌尿器科 泌尿器科 泌尿器科
  • 在瘤学瘤学.
  • 医疗成像医学成像

背景情况:

  • 系统活检与有针对性的活检一起使用,因为临床显著癌症的错误率为15-20%.
  • 对遗漏癌症的担忧影响了诸如系统活检和偏好全腺治疗等干预措施.

研究的目的:

  • 审查MRI隐形前列腺病变的基因组和临床数据.
  • 评估MRI隐形前列腺癌的临床意义和基因组概况.

主要方法:

  • 审查最近的基因组和临床研究.
  • 分析数据,将遗传异常与癌症的可见性,侵入性和转移性联系起来.

主要成果:

  • 在MRI看不见的前列腺病变,尽管"临床上显著"的组织学,是基因组和临床上有利.
  • 导致癌症可见性的遗传异常也与侵袭性有关;看不见的癌症通常是惰的.

结论:

  • 对大多数患者来说,可以放弃系统活检.
  • 用成像和重复向活检检查MRI进展的监测是患者利益的首选策略.

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