在老年患有肉症的老年患者中,术后不良结果
Yitian Yang1, Mingyang Sun1, Wan-Ming Chen2,3
1Department of Anesthesiology and Perioperative Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, China.
BMC geriatrics
|June 27, 2024
概括
在接受重大手术的患者中, Sarcopenia显著增加了30天和90天死亡率以及包括肺炎和出血在内的重大并发症的风险. 手术前的肉类是不良术后结果的独立风险因素.
科学领域:
- 老年医学 老年医学
- 外科手术的结果
- 临床营养学 临床营养学
背景情况:
- 随着年龄的增长,肌肉质量和力量的损失被认为是老年人的重大健康问题.
- 它对术后结果的影响,特别是在接受重大手术的患者中,需要进一步调查.
研究的目的:
- 为了比较30天和90天的不良术后结果和老年患者与未患有肉症进行重大手术之间的死亡率.
- 为了确定 sarcopenia 是否是这些结果的独立风险因素.
主要方法:
- 进行了一项倾向分数匹配 (PSM) 队列研究.
- 接受重大手术的老年患者被分为两组:患有和没有手术前的肉症 (1:4比率).
- 分析了30天和90天的不良术后结果和死亡率.
主要成果:
- 患有手术前肉症的患者表现出显著更高的30天死亡率 (aOR=1.25) 和肺炎,出血和败血症等重大并发症的风险.
- 肉患者也面临着显著更高的90天死亡率 (aOR=1.50) 和主要并发症的风险,包括肺炎,出血和败血症.
- 标识了萨科佩尼亚作为30天和90天不良术后结果和死亡率的独立风险因素.
结论:
- 手术前的肉类是重大手术后不良后果和死亡率的重要独立风险因素.
- 这些结果包括肺炎,术后出血和30天和90天内的败血症的风险增加.
- 在选择性手术之前,建议进行纠正肉类的干预,改善吞,并增强呼吸道肌肉功能,以减少并发症和手术死亡率.
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