百分比最终高度是一种新的方法,可以识别不同种族的美国儿童发育速度之间的差异
Tristen N Taylor1,2, Ally A Yang3, Tiffany M Lee2
1Department of Orthopaedic Surgery, Texas Children's Hospital, Houston, TX.
Journal of pediatric orthopedics
|June 28, 2024
概括
骨发育因种族而异,与高加索儿童相比,黑人和西班牙裔儿童的骨年龄 (BA) 较晚. 这些发现凸显了对种族特定生长评估的需要,超越了旧的标准.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 骨的发育 骨的发育
- 放射性评估的放射性评估
背景情况:
- 基于1926-1942年高加索手X射线的格鲁里奇和派尔 (G&P) 地图是骨发育的历史标准.
- 现代儿科人口表现出多样化的祖先,需要更新的骨发育评估.
- 这项研究调查了不同种族群体的骨发育模式,作为百分比最终高度 (PFH) 的函数.
研究的目的:
- 为了比较现代高加索,黑人,西班牙裔和亚洲儿童的骨年龄 (BA) 和时间年龄 (CA).
- 分析骨成熟差异作为种族群体之间的百分比最终身高 (PFH) 的函数.
- 使用当代数据识别骨发育中的潜在基于种族的变异.
主要方法:
- 对498名儿童 (53名亚裔,83名黑人,190名西班牙裔,172名白人) 的手部X射线和身高测量的回顾性审查.
- 计算百分比最终身高 (PFH),并比较种族之间的骨年龄 (BA) 和时间年龄 (CA).
- 针对CA和BA的PFH的多项式回归建模;在第85个PFH中比较平均年龄;根据桑德斯阶段进行分析.
主要成果:
- 与白人儿童相比,黑人和西班牙裔儿童的骨年龄 (BA) 显著提升 (P <0.001).
- 在第85个PFH时,黑人男性和西班牙裔女性比白人同行更年轻地达到这个阶段.
- 西班牙裔和黑人男性在第85 PFH 时显示出比白人男性更大的 BA;与黑人女性相比,亚洲女性也显示出高级的 BA.
结论:
- 黑人和西班牙裔儿童的骨龄 (BA) 显著超过了黑人和西班牙裔儿童的年龄 (CA).
- 骨成熟的种族特异性变化很明显,特别是在最终身高的第85个百分位.
- 目前的发现表明,需要对种族进行调整的骨发育评估,并可能修订生长图谱.
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