墨西哥成年人患有先天性心脏病的心脏代谢风险因素
Edgar García-Cruz1, Daniel Manzur-Sandoval2, Rodrigo Gopar-Nieto3
1Congenital Heart Disease Unit, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
JACC. Advances
|June 28, 2024
概括
患有先天性心脏病 (ACHD) 的成年人面临高水平的心脏代谢风险,根据心脏缺陷的复杂性而有所不同. 持续监测新陈代谢健康对于这个不断增长的人口至关重要.
科学领域:
- 心脏病学 心脏病学
- 代谢健康 代谢健康
- 公共卫生 公共卫生
背景情况:
- 患有先天性心脏病 (ACHD) 的成年人生存时间更长.
- 增加的生存率导致心脏代谢因素和慢性疾病的风险更高.
- 了解这些风险对于管理ACHD患者的长期健康至关重要.
研究的目的:
- 在ACHD人群中描述心脏代谢风险概况.
- 调查这些风险概况与先天性心脏病 (CHD) 病变的复杂性之间的关系.
- 为ACHD个人提供有针对性的健康监测策略的信息.
主要方法:
- 在墨西哥城对1171名ACHD患者进行了横截面研究.
- 患者根据心血管疾病病变的复杂性进行分类:轻度,中度和严重.
- 使用后勤回归模型来评估心脏代谢风险因素和心脏病严重程度之间的关联.
主要成果:
- 低高密度脂蛋白胆固醇 (55%),胰岛素抵抗 (54.5%) 和糖尿病前期 (52.4%) 是普遍存在的.
- 轻度和中度心脏病与更高的肥胖率和代谢综合征有关.
- 严重的心脏病与高尿血和亚临床甲状腺功能障碍的增加相关,以及代谢综合征,糖尿病前期和高血压风险的降低.
结论:
- 墨西哥ACHD患者表现出高心脏代谢风险因子的流行率.
- 根据心脏病病变的复杂性,风险概况有很大差异.
- 这些发现强调了在ACHD人群中持续进行代谢健康监测的必要性.
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