在免疫功能低下的主体中出现新肺空隙的渐进性脑病变
Marika Orlov1, Andrew T Pham1, Dan Merrick1
1Department of Pulmonary Sciences and Critical Care Medicine (M. O., T. M., and A. K.), the Department of Medicine (A. T. P.), the Department of Pathology (D. M.), the Department of Radiology (M. W.), University of Colorado Anschutz Medical Campus, Aurora, CO; and the Department of Infectious Diseases (S. S.), University of Nebraska Medical Center, Omaha, NE.
一名免疫抑制的移植接受者在前往墨西哥后出现了进展性神经症状. 这一案例突出显示了一种罕见的真菌感染,在免疫功能低下的患者中模仿脑膜炎.
科学领域:
- 传染性疾病 传染性疾病
- 腎臟病學 (nephrology) 是一種醫學專業.
- 神经学 神经学
背景情况:
- 一名48岁的男性接受了免疫抑制剂的移植,出现了一个月的神经症状.
- 症状包括头痛,疲劳,难以找到单词,夜间出汗,最近去墨西哥中部旅行.
- 以前对疑似脑膜炎的治疗是无效的.
研究的目的:
- 在免疫抑制患者中报告罕见的真菌感染病例.
- 讨论这种感染的诊断挑战和临床表现.
主要方法:
- 病例报告详细介绍患者病史,临床表现和实验室发现.
- 对诊断工作和治疗过程的审查.
主要成果:
- 患者呈现出迷失方向,低血和神经系统缺陷.
- 实验室测试显示没有超治疗性免疫抑制剂水平,排除了药物毒性.
- 临床图片表明是一种机会性感染.
结论:
- 免疫抑制的个体,特别是脏移植接受者,有机会性感染的风险.
- 这种人群的神经症状需要对不常见的病原体进行彻底的调查.
- 及时诊断和治疗对于管理这种感染至关重要.
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