种族和民族与阻塞性冠状动脉疾病的关联
Jasjit Rooprai1, Feng Qiu1, Joan Porter1
1ICES, Toronto, Ontario, Canada.
JACC. Advances
|June 28, 2024
概括
与白人患者相比,患有冠状动脉疾病 (CAD) 的南亚和东亚患者患有阻塞性CAD的几率更高. 这凸显了将种族和民族纳入CAD风险预测模型的必要性.
科学领域:
- 心脏病学 心脏病学
- 健康差异 在健康上的差异
- 医学研究 医学研究
背景情况:
- 在稳定的冠状动脉疾病 (CAD) 中,冠状动脉扫描的患者选择依赖于阻塞性CAD的预测概率.
- 关于CAD患病率和严重程度的种族和民族差异的数据有限.
研究的目的:
- 调查种族,种族和稳定的CAD患者冠状动脉阻塞的存在之间的关联.
主要方法:
- 在加拿大安大略省 (2012-2019) 进行首次冠状动脉血管造影的71,199名患者的分析.
- 种族和种族数据是医生识别的.
- 阻塞性CAD定义为左主狭窄 ≥50%或主要心上血管狭窄 ≥70%.
- 用于评估独立关联的多变量逻辑回归.
主要成果:
- 南亚 (SA) 患者 (14.0%) 是最年轻的,最有可能患有阻塞性CAD (46.9%),相比之下,东亚 (EA) (43.0%) 和白人患者 (37.9%).
- 在SA患者中,阻塞性CAD的调整后几率比白人患者高67% (OR 1.67).
- 与白人患者相比,EA患者也显示出阻塞性CAD的调整后几率增加 (OR 1.40).
- 在SA患者中,三血管CAD的患病率最高 (13.4%).
结论:
- 较年轻的南亚患者出现阻塞性CAD的可能性更高.
- 种族和种族是与阻塞性CAD相关的重要因素.
- 将种族和种族数据整合到风险预测工具中可能会提高冠状动脉阻塞的检测.
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