用乌帕达西提尼布成功治疗耐火性全般化瘤
Alexis Coican1, Abigail Meckley1, Nathan Sagasser2
1Department of Graduate Medical Education, Orange Park Medical Center, Orange Park, FL 32073, USA.
Case reports in dermatological medicine
|June 28, 2024
概括
泛性状颗粒瘤 (GA) 很难治疗. 这项研究表明,口服上达西替尼在两名女性中有效地解决了反性GA,提供了一个新的治疗选择.
科学领域:
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
- 药理学 药理学是指药理学的学科.
背景情况:
- 泛性粒状瘤 (GA) 是一种罕见的,鲜为人知的皮肤疾病,影响患者的比例高达15%.
- 一般性GA的治疗通常是实验性的,并且由于传统疗法的有效性有限而令人丧.
相关概念视频
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel Disease...
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2 (COX-2),...


