乳球菌G423通过调节肠道微生物群和代谢物来改善 brojlers 的生长性能和脂质代谢
Mi Wang1, Wei Ma1, Chunqiang Wang1
1College of Animal Husbandry and Veterinary Medicine, Jinzhou Medical University, Jinzhou, China.
Frontiers in microbiology
|June 28, 2024
概括
通过改变肠道微生物群和代谢物,乳球菌G423补充剂改善了 brojler 的生长和脂质代谢. 这种益生菌增强了平均每日增益,并降低了料转化率和腹部脂肪.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 营养科学 营养科学
背景情况:
- 肠道微生物群在宿主新陈代谢和健康中起着至关重要的作用.
- 益生菌,如乳球菌,越来越多地被探索,因为它们有可能调节肠道微生物群并改善动物的表现.
- 了解特定益生菌菌株对肉生理学的影响,对于优化生产至关重要.
研究的目的:
- 为了研究乳球菌G423对 brojlers的生长性能和脂质代谢的影响.
- 探索肠道微生物群和代谢物的调节由乳球菌G423.3.
- 确定乳球菌G423的最佳剂量,以改善肉的健康和生产力.
主要方法:
- 总共有640只肉被分为四组:对照组,低剂量乳球菌G423 (Lac_L),高剂量乳球菌G423 (Lac_H) 和抗生素 (ABX).
- 测量了生长性能参数 (ADG,ADFI,FCR) 和尸体特征.
- 使用ELISA分析了血清脂质概况 (HDL,TC,LDL,TG).
- 用16S rRNA测序和qPCR分析肠道微生物组成,使用LC-MS分析代谢物.
主要成果:
- 高剂量的Lactococcus G423显著改善了 brojlers的平均每日增益 (ADG) 和料转换率 (FCR).
- 腹部脂肪百分比和血清甘油三 (TG),总胆固醇 (TC) 和低密度脂蛋白 (LDL) 水平被乳球菌G423.3显著降低.
- 乳球菌G423改变了肠道微生物群的组成,增加了Firmicutes和Lactobacillus的丰富性,并调节了参与酸和氨酸代谢的关键代谢物.
结论:
- 乳球菌G423补充剂有效地改善肉的生长性能和脂质代谢.
- 益生菌调节肠道微生物群和代谢物概况,有助于改善肉的健康和生产力.
- 乳球菌G423显示出作为可持续肉生产的料添加剂的潜力.
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