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与单心室息相关的累积住院费用

Michael L O'Byrne^1,2,3, Kimberly E McHugh⁴, Jing Huang^1,5

¹Division of Cardiology, The Children's Hospital of Philadelphia and Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

|June 28, 2024

概括

这项研究发现,在五年内,右心室到肺动脉分流 (RVPAS) 和修改的布拉洛克-陶西格-托马斯分流 (MBTTS) 之间的总医院费用没有显著差异. 长期成本强调了需要改善单心室重建患者的治疗结果.

科学领域:

儿童心脏病学儿童心脏病学
生产性心脏病手术手术生产性心脏病
卫生经济学卫生经济学

背景情况:

单心室重建 (SVR) 试验表明右心室到肺动脉转移 (RVPAS) 与修改的布拉洛克-陶西格-托马斯转移 (MBTTS) 的1年生存率优越,尽管在随后的随访中没有.
成本分析对于评估与不同手术干预相关的价值和发病率至关重要.

研究的目的:

为了在单心室患者中比较RVPAS和MBTTS之间的累计医院费用.
评估成本效益,并确定影响这一群体医疗保健支出的因素.

主要方法:

结合了来自SVR试验的临床数据和来自儿科健康信息系统数据库的成本数据.
在干预后1,3年和5年,比较RVPAS和MBTTS之间的累积医院费用和每天生存成本.
利用多变量模型来探索患者层面的因素与成本之间的关联.

主要成果:

在RVPAS和MBTTS之间在1,3或5年内没有观察到总成本或每天活费的统计学上显著差异.
在没有移植的幸存者中,RVPAS在1年后显示出更高的成本,但随着时间的推移,这种差异减少了.
动脉缩和早产被确定为与每天生存成本增加相关的因素.

结论:

在RVPAS和MBTTS干预措施之间,医疗保健总成本没有显著差异.
显著的纵向成本强调了对提高单心室重建患者的临床结果的战略的急需.

关键词:

经济分析经济分析低可塑性左心综合征是什么研究结果研究成果.儿科儿科儿科儿科

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