在刺激性肠综合征的随机饮食试验中,招募过程的挑战
Bodil Roth1,2, Bodil Ohlsson1,2
1Department of Internal Medicine, Skåne University Hospital, Malmö, 20502, Sweden.
F1000Research
|June 28, 2024
概括
招募刺激性肠综合征 (IBS) 饮食试验的参与者,如低FODMAP或SSRD,由于纳入率低,这证明具有挑战性. 社交媒体成为这些IBS干预措施最有效的招聘道.
科学领域:
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
- 公共卫生 公共卫生
背景情况:
- 刺激性肠综合征 (IBS) 在全球影响了4%,低FODMAP和SSRD等饮食干预措施显示出有效性.
- 本研究的重点是对一项随机对照试验的招聘过程,该试验比较了低FODMAP和SSRD饮食.
- 试验设计包括4周的干预和5个月的随访期.
研究的目的:
- 描述一项针对IBS患者的随机饮食试验的招募策略和结果.
- 评估不同招募方法对IBS饮食干预的临床试验的有效性.
主要方法:
- 在斯卡内,成年IBS患者 (18-70岁) 被随机分配到低FODMAP或SSRD饮食中.
- 招聘利用讲座,初级医疗保健外展,社交媒体活动和医疗记录识别.
- 这项研究共招募了155名IBS患者.
主要成果:
- 尽管开展了广泛的推广工作,但招聘的整体包容率很低.
- 社交媒体活动产生了最高比例的符合条件和愿意参与者 (42.7%).
- 从医疗记录中直接接触导致了6.5%的纳入率.
结论:
- 该研究强调了招募IBS饮食干预试验的重大挑战.
- 社交媒体似乎是招募IBS患者参加临床试验的最有效道.
- 优化招募策略对于未来IBS饮食干预研究的成功至关重要.
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