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银酸:一种用于治疗结直肠癌的免疫调节剂

Jianan Qian^1,2, Yanyu Jiang³, Hongyi Hu¹

¹Department of Gastroenterology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Frontiers in pharmacology

|June 28, 2024

概括

帕纳克斯人参中的金色化物通过调节瘤微环境 (TME) 来治疗结直肠癌 (CRC) 是有前途的. 本综述探讨了它们作为补充疗法的潜力,以增强CRC患者的免疫力和延长CRC患者的存活时间.

科学领域:

药理学药理学是指药理学的学科.
在瘤学瘤学.
免疫学免疫学免疫学

背景情况:

潘纳克斯人参中的活性化合物金色诺化物以其治疗潜力而闻名.
结肠直肠癌 (CRC) 治疗是一个活跃的研究领域,对补充疗法感兴趣.
瘤微环境 (TME) 在癌症进展和治疗反应中发挥着关键作用.

研究的目的:

系统地审查人参酸在调节结直肠癌瘤微环境 (TME) 中的作用.
在CRC TME中探索金氏化物对免疫反应,肌体细胞和癌细胞特征的影响.
讨论人参酸在CRC治疗中的临床应用和未来前景.

主要方法:

系统性文献审查关于人参和CRC的实验研究.
对研究的分析,重点是关于人参化物对TME组件和功能的影响.
对临床数据的评估,关于在CRC患者中使用金丝诺的疗效.

主要成果:

银化物增强TME内的抗瘤免疫反应.
它们抑制了与癌症相关的 stromal 细胞的激活.
银化物改变结直肠癌细胞的关键特征,并影响TME的物理化学特性.

结论:

银化物在调节CRC TME方面表现出显著的潜力.
它们在增强患者免疫力和延长生存时间方面提供了好处.
银化物代表着对结直肠癌的有前途的补充和替代治疗策略.

关键词:

结肠直肠癌是什么意思类类类类.免疫调节免疫调节免疫调节帕纳克斯人参 (Panax ginseng) 是一种人参.传统的中国医药传统的中国医药.瘤微环境是一个微环境.

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