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Updated: Jun 22, 2025

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules
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增强Hi-C接触矩阵与摩座的循环检测:一个多视图扩散模型.

Tangqi Fang1, Yifeng Liu1, Addie Woicik1

  • 1Paul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, WA 98195, United States.

Bioinformatics (Oxford, England)
|June 28, 2024
PubMed
概括

摩座使用一种新的机器学习方法来增强低覆盖率的Hi-C数据,改善了关键基因组结构 (如染色体循环) 的识别. 这种方法提供了一种具有成本效益的方法来实现高分辨率的3D基因组架构分析.

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The extracellular matrix or ECM holds cells together to form a tissue and allows the cells within the tissue to communicate. ECM comprises proteins such as fibronectin, collagen, laminin, etc. The most abundant protein in this space is collagen. Collagen fibers are interwoven with carbohydrate-containing protein molecules called proteoglycans. ECM allows cell migration and provides a structural scaffold at cell adhesion that anchors the cell when the extracellular matrix proteins interact with...
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