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Updated: Jun 22, 2025

A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors
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代表突变用于预测癌症药物反应.

Patrick Wall1, Trey Ideker1,2,3

  • 1Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, United States.

Bioinformatics (Oxford, England)
|June 28, 2024
PubMed
概括

通过使用定量突变得分而不是简单的基因突变状态来改善预测癌症药物反应. 这种方法提高了针对癌症向治疗的模型性能和理解.

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