在短期极寒暴露后,基线血压变化和左心功能之间的关联
Renzheng Chen1,2, Qian Yang1, Yabin Wang1
1National Clinical Research Center for Geriatric Diseases, The Second Medical Center, Chinese PLA General Hospital, Beijing, China.
Journal of clinical hypertension (Greenwich, Conn.)
|June 28, 2024
概括
极端寒冷的暴露会影响心脏功能. 血压的基线变化,包括变化系数 (CV) 和平均真实变化 (ARV),可以预测冷暴露后喷射分数 (EF) 的变化.
科学领域:
- 心脏病学 心脏病学
- 环境医学 环境医学
- 生理学 生理学 生理学
背景情况:
- 极端寒冷的暴露是已知的心脏压力因素.
- 了解心脏适应寒冷对公共健康至关重要.
研究的目的:
- 为了确定极端寒冷暴露期间心血管变化的危险因素.
- 评估基线心血管指标对寒冷暴露后心脏功能的预测价值.
主要方法:
- 70名受试者接受了24小时的门诊血压监测和心声回声仪,在一天暴露于-17至-34°C之前和之后.
- 分析包括射出分数 (EF) 变化,血压变化 (BPV) 度量,如变化系数 (CV) 和平均真实变化 (ARV).
主要成果:
- 41名受试者显示EF增加,而29人显示EF暴露后减少.
- 较低的基线血压CV和ARV与EF增加有关.
- 基线血压变化 (CV和ARV) 独立预测EF下降.
结论:
- 基线心血管指标,特别是血压变化,与极度寒冷暴露后左心功能 (EF) 的变化密切相关.
- 血压变化是寒冷环境中心脏功能变化的有效预后指标.
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