肠道微生物群:对于改善动脉样硬化的食植物化学物质来说,它是一个优秀的运营者
Jian Ai1,2, Xin Tang1,2, Bingyong Mao1,2
1State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, China.
Critical reviews in food science and nutrition
|June 28, 2024
概括
食中向肠道微生物群的植物化学物质显示出对治疗动脉样硬化 (AS) 的承诺. 了解肠道细菌的植物化学新陈代谢为开发抗atherogenic 剂提供了新的途径.
科学领域:
- 微生物学 微生物学
- 药理学 药理学是指药理学的学科.
- 营养科学 营养科学
背景情况:
- 动脉样硬化 (AS) 越来越多地与肠道微生物群组成有关.
- 饮食中的植物化学物质正在通过调节肠道细菌来探索它们在AS中的治疗潜力.
研究的目的:
- 审查肠道微生物群和AS之间的关系.
- 总结关于饮食中的植物化学物质如何通过肠道微生物群操纵影响AS的证据.
- 探索植物化学代谢物的抗动脉样硬化作用.
主要方法:
- 关于肠道微生物群,AS和饮食中的植物化学物质的文献评论.
- 对所选植物化学品微生物代谢途径的分析.
- 对植物化学代谢物对AS的分子机制的研究.
主要成果:
- 饮食中的植物化学物质可以通过改变肠道微生物群来改善AS.
- 特定的肠道细菌和酶参与了植物化学生物转化.
- 来自植物化学品的代谢物表现出抗动脉样硬化性质.
结论:
- 微生物群依赖的食植物化学疗法是AS管理的可行策略.
- 了解"植物化学 - 微生物群 - 生物转化"轴对于新型抗异地原体药物发现至关重要.
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