通过DPR介导的H2O2耐药性有助于链球菌在囊性纤维化气道模型系统中的存活

Rendi R Rogers1, Christopher A Kesthely1, Fabrice Jean-Pierre1

  • 1Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.

PubMed
概括

血球菌需要对反应性氧物种进行保护,以便在囊性纤维化肺部生物膜中生存. 与DNA结合的费里丁类蛋白Dpr和调节器PerR是这种保护的关键,特别是对Pseudomonas aeruginosa.

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