童年空气污染暴露与成人时自我报告的支气管炎症状有关
Erika Garcia1, Zoe H Birnhak1, Scott West1
1Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California; and.
儿童暴露于二氧化 (NO2) 和颗粒物 (PM10) 与成人支气管炎症状有关. 这些影响即使考虑到儿童呼吸系统问题,特别是儿童喘患者,也会持续下去.
科学领域:
- 环境健康 环境健康
- 呼吸系统医学 呼吸系统医学
- 流行病学 流行病学
背景情况:
- 儿童空气污染对成人呼吸系统健康的长期影响尚未得到充分研究.
- 了解儿童的呼吸系统疾病是否调解这些影响至关重要.
研究的目的:
- 评估儿童暴露于空气污染物和成人支气管炎症状之间的关联.
- 为了确定儿童的呼吸系统健康是否会影响这种关系.
主要方法:
- 利用了来自南加州儿童健康研究的数据.
- 根据儿童居住史,估计暴露于二氧化 (NO2),臭氧和PM10.
- 通过问卷评估成人支气管炎症状,并使用逻辑回归分析相关性,并根据儿童呼吸系统健康进行调整.
主要成果:
- 成年人的支气管炎症状与童年暴露于NO2和PM10有关.
- 每个1-SD增加的几率比为NO2的1.69和PM10.0的1.51.
- 在调整为童年支气管炎症状或喘后,关联仍然显著,并且在患有喘的儿童中更强.
结论:
- 儿童暴露于NO2和PM10与成人支气管炎症状有关.
- 观察到的关联不仅仅可以通过儿童的呼吸系统健康来解释.
- 儿童喘加剧了儿童暴露于空气污染和成人支气管炎症状之间的联系.
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