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相关概念视频

Menopause01:28

Menopause

154
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
154
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

339
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
339
Target Cell Response to Hormones01:22

Target Cell Response to Hormones

3.0K
Hormones intricately bind to receptors on the surface or within target cells, initiating a cascade of cellular responses.
Notably, the cellular response can be regulated by altering the number of receptors expressed in the cell. For example, prolonged exposure to elevated hormone levels results in a gradual decline or down-regulation in the number of receptors for that specific hormone on the cell surface. Conversely, in response to low hormone levels, cells may use up-regulation, producing an...
3.0K
Oogenesis02:07

Oogenesis

63.6K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
63.6K
Hormonal Control of the Ovarian Cycle01:30

Hormonal Control of the Ovarian Cycle

461
The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...
461
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

347
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
347

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使用含有乙inylestradiol-norgestimate的药丸可以改善女性的性行为,尽管循环中的雄激素减少:试点研究

Maurizio Guida1, Luciano Quercitelli1, Pasquale De Franciscis2

  • 1University Federico II, Naples, Italy.

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception
|June 28, 2024
PubMed
概括

这项研究发现,含有乙inyl-estradiol和norgestimate的联合口服避孕药 (COCs) 改善了女性的性欲得分. 尽管丸激素和DHEAS显著下降,但性功能在短期内并没有下降.

关键词:
这就是DHEASAS.没有估计的标准.类激素是一种类激素.避孕药可以作为避孕药.利比多是一种性欲.在性爱中,性爱是性爱.性欲性质性质性质性质性质性质性质性质性测试剂 测试剂 测试剂 测试剂

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科学领域:

  • 生殖内分泌学 生殖内分泌学
  • 药理学 药理学 是一个学科.

背景情况:

  • 联合口服避孕药 (COCs) 广泛用于避孕.
  • 对女性性和雄激素水平的COC的影响需要进一步调查.

研究的目的:

  • 评估含有乙inyl-estradiol (EE) 和norgestimate (NGM) 的联合口服避孕药 (COC) 对女性性行为的短期影响.
  • 评估这种COC对循环中的雄激素水平的影响,特别是 (T) 和脱乙硫酸 (DHEAS).

主要方法:

  • 一项为期6个月的研究,涉及36名女性使用单相药丸,EE为35μg,NGM为0.250mg.
  • 在治疗前和治疗后测量了麦考伊女性性质问卷 (MFSQ) 和T和DHEAS的血清水平.

主要成果:

  • 观察到MFSQ得分的显著改善 (p < 0.0001),不包括阴道滑领域.
  • 同时发现血清丸激素 (-4.45%,p < 0.0001) 和DHEAS (-19.41%,p < 0.0001) 的显著下降.

结论:

  • 含有COC的乙inyl-estradiol/norgestimate (EE/NGM) 显示对女性性行为产生短期的非有害影响.
  • 在使用COC期间,女性的性行为是多因素的,不仅仅取决于雄激素水平.