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Updated: Jun 22, 2025

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
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Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade

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通过激活α2B-上腺素受体,持续缓解自身免疫

Veena Viswanath1, Shruti Mistry1, Sara Cabrera-Ghayouri1

  • 1Ophthalmology Discovery Research, AbbVie Inc., Irvine, CA.

Journal of immunology (Baltimore, Md. : 1950)
|June 28, 2024
PubMed
概括

一种新型的激动剂,AGN-762,选择性地准α2B/α2C-上腺体受体,通过调节T调节细胞而减少小鼠模型中的自身免疫性疾病,没有常见的副作用.

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