用家用设备对抗COVID-19的光生物调制治疗:一项针对有效性和安全性的随机对照试验
Lew Lim1, Nazanin Hosseinkhah1, Mark Van Buskirk2
1Vielight Inc., Toronto, ON, Canada.
Photobiomodulation, photomedicine, and laser surgery
|June 28, 2024
概括
在家用光生物调节疗法 (PBMT) 显著加快了早期COVID-19症状的恢复速度. 这种安全的治疗方法对症状超过7天的患者没有益处.
科学领域:
- 医学研究 医学研究
- 治疗方法 治疗方法
- 呼吸系统药物 呼吸系统药物
背景情况:
- 光生物调制疗法 (PBMT) 使用红色和近红外光来产生治疗效果.
- 在呼吸系统疾病和COVID-19症状管理方面,PBMT已经显示出有前途.
- 自主在家用PBMT治疗COVID-19的安全性和有效性需要进行调查.
研究的目的:
- 为了评估在COVID-19患者的在家,自我管理的PBMT的安全性和有效性.
- 为了确定PBMT是否能改善恢复时间并减少症状严重程度.
主要方法:
- 一项随机对照试验 (RCT) 涉及199名COVID-19患者 (18-65岁).
- 参与者被分配到标准护理 (SOC) 或SOC加PBMT使用Vielight RX Plus设备.
- 主要终点是基于威斯康星州上呼吸道症状调查 (WURSS-44) 的恢复时间.
主要成果:
- 患有≤7天症状的患者在PBMT治疗中恢复得显著更快 (中位数为18天与21天,p=0.050).
- 在症状持续时间≥7天的患者中没有观察到显著改善.
- 与对照组不同的是,PBMT组没有死亡或严重不良事件 (SAE),而对照组 (1死亡,3SAE).
结论:
- 家庭PBMT是一种安全有效的治疗方法,可加速COVID-19早期症状 (≤7天) 的患者的康复.
- 对于持续超过七天的COVID-19症状患者,PBMT没有显示出显著的益处.
- 进一步的研究可能会探索PBMT在治疗其他呼吸系统疾病中的作用.
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