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在中国,暴露于热量和与痴呆相关的死亡率
1School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, NHC Key Lab of Health Technology Assessment, Fudan University, Shanghai, China.
JAMA network open
|June 28, 2024
概括
夜间和白天的热量都会增加与痴呆症相关的死亡,夜间的热量造成的负担更大. 有针对性的干预措施对于减轻极端高温风险和保护弱势群体免受与热相关的痴呆死亡率至关重要.
科学领域:
- 环境流行病学环境流行病学
- 公共卫生 公共卫生
- 老年学是指老年学的学科.
背景情况:
- 现有的研究将日常热量暴露与痴呆症的结果联系起来.
- 在了解夜间与白天热量对痴呆相关死亡率的不同影响方面存在差距.
研究的目的:
- 量化因短期夜间和白天暴露于热量的痴呆相关死亡风险和负担.
- 在这些关联中识别潜在的效果修改.
主要方法:
- 一项全国性的病例交叉研究分析了中国132,573例 (2013-2019) 痴呆相关死亡.
- 新的指标,热夜过量 (HNE) 和热日过量 (HDE),用于评估热强度.
- 使用有条件后勤回归与分布式滞后非线性模型.
主要成果:
- 无论是在夜间还是白天暴露于热量,都与痴呆相关的死亡风险增加有关.
- 夜间热的影响持续了6天;白天热的影响持续了10天以上.
- 极端夜间热量 (HNE) 与极端白天热量 (HDE) 相比,显示出更大的归因负担.
- 女性,75岁以上的个人和教育程度较低的人表现出更高的易感性.
- 区域差异被注意到,南部人口对夜间热量更敏感,北部人口对白天热量更敏感.
结论:
- 夜间和白天的热量显著增加了与痴呆相关的死亡风险.
- 暴露在夜间的热量带来了更大的痴呆症死亡总体负担.
- 特定时间的公共卫生干预措施对于减轻极端高温风险和降低痴呆症死亡率至关重要.
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