相关实验视频

Updated: Jun 22, 2025

Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position

Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position

Published on: August 17, 2017

为80岁及以上的成年人提供部骨折风险评估工具

Kristine E Ensrud^1,2,3, John T Schousboe^4,5, Carolyn J Crandall⁶

¹Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis.

JAMA network open

|June 28, 2024

概括

像FRAX和Garvan这样的骨折风险评估工具没有改善80岁以上成年人的部骨折预测. 仅仅是股骨部骨矿物质密度 (FNBMD) 是一个更好的预测指标,尽管临床医生应该考虑骨质密度,预期寿命和患者的偏好.

科学领域:

老年学是一门学科.
整形外科整形外科整形外科
流行病学流行病学

背景情况:

80岁及以上的成年人经历了大量的关节骨折.
目前的骨折风险评估工具在老年人群中表现不确定.

研究的目的:

为了比较仅使用骨折风险评估工具 (FRAX),Garvan骨折风险计算器和大腿骨矿物质密度 (FNBMD) 的5年部骨折预测准确度.
评估这些工具在80岁及以上的成年人中的效果.

主要方法:

对3项前性队列研究的预测分析,涉及8890名80岁以上的参与者.
使用FRAX和Garvan模型 (带有和没有FNBMD) 计算5年关节骨折概率.
评估模型使用AUC进行区分,并通过比较观察和预测的概率进行校准.

主要成果:

仅仅部部骨矿物质密度 (FNBMD) 在女性和男性中,与FRAX和Garvan相比,显示出优异的歧视.
在中等风险个体中,FRAX适度低于预测的关节骨折风险.
加尔文明显高估了高风险个体的关节骨折风险.

结论:

无论是FRAX还是Garvan,即使结合FNBMD,在80岁以上的成年人中,与单独使用FNBMD相比,FRAX和Garvan都没有改善5年关节骨折预测.
临床医生应考虑FNBMD,预期寿命和患者的偏好,以决定在老年人中预防关节骨折.
为老年人开发改进的骨折预测工具是有必要的.

更多相关视频

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

Published on: January 31, 2025

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

相关概念视频

Bone Disorders

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...

Flail Chest-II

Flail Chest-II

Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History: