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Updated: Jun 22, 2025

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib
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阿法丁尼布加PEM和CBDCA克服了EGFR突变NSCLC中与高血栓蛋白-1表达的奥西默丁尼布耐药性

Naomi Onda1, Shinji Nakamichi1, Mariko Hirao1

  • 1Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.

Cancer science
|June 28, 2024
PubMed
概括

在EGFR突变肺癌中可以克服奥西默提尼布的耐药性. 与阿法替尼,卡博普拉丁和佩姆雷克塞德的联合治疗有效地抑制了耐药模型中的瘤入侵和生长.

关键词:
皮肤上生长因子受体.表皮细胞转变为介质酶的过渡.矩阵金属蛋白质酶的结构.其他非小细胞肺癌.血小板蛋白 1 1

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