[代谢综合征和献血者的代谢特征]
Pedro Aro1, Rodrigo Paredes2, Grace Tello3
1HOSPITAL NACIONAL CAYETANO HEREDIA. pedro.aro.g@upch.pe.
概括
代谢综合征 (MS) 在献血者中很常见,影响了43.6%的个人. 在这个人群中早期检测可以帮助识别心血管风险因素.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 代谢综合征 (MS) 与心血管风险增加有关.
- 献血者代表了一个看似健康的群体,但他们的心脏代谢健康状况往往没有得到评估.
- 关于在献血者群体中MS及其组成部分的患病率的数据有限.
研究的目的:
- 为了确定代谢综合征 (MS) 的频率及其相关的代谢特征在献血者中.
- 调查特定的MS组件的患病率,包括高甘油三血症,腹部肥胖症和低高密度脂蛋白 (HDL) 胆固醇.
- 探索MS之间潜在的关联,其特征,以及性别和年龄等人口因素.
主要方法:
- 在秘鲁利马的Cayetano Heredia医院对244名年龄在18-55岁的献血者进行了横截面研究.
- 代谢综合征 (MS) 诊断遵循成人治疗小组III (ATP III) 标准.
- 使用双变量分析来检查MS,代谢特征和性别之间的关系,显著程度为5%.
主要成果:
- 43.6%的献血者被诊断出患有代谢综合征 (MS).
- 最常见的特征是高甘油三血症 (54.5%),腹部肥胖 (51.2%),低高密度脂蛋白 (HDL) 胆固醇 (48.8%).
- 多发性硬化在40-49岁年龄组中最常见 (14.3%). 过高甘油三和高血压在男性中更常见,而较低的HDL在女性中更为普遍.
结论:
- 献血者具有较高的代谢综合征 (MS) 患病率.
- 对多发性硬化症的献血者进行查可能有助于早期识别心血管风险因素.
- 建议将多发性硬化症检测纳入看似健康个体的初级保健策略.
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