异常长寿的生命历程途径:1921年洛西安出生队列的证据
Janie Corley1, Alison Pattie1, G David Batty2
1Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, UK.
概括
成功的衰老和长寿受到整个生命周期的因素的影响. 认知功能,身体健康和生活方式的选择显著影响生存时间,早期生活因素起到间接作用.
科学领域:
- 老年学是一门学科.
- 流行病学 流行病学
- 寿命研究的研究.
背景情况:
- 长寿是一个复杂的特征,受到从出生起的因素的影响.
- 关于在单一群体内将终身暴露与长寿联系在一起的途径的研究有限.
研究的目的:
- 调查生命过程因素与寿命之间的关联.
- 探索早期,中年和晚年因素如何影响生存时间.
主要方法:
- 分析了1921年洛西安出生队伍中79岁的547名社区成年人.
- 在24年的死亡跟踪中使用了考克斯的比例危险和结构方程 (路径) 模型.
- 检查了早期生活 (社会阶级,智商,教育),中年 (社会阶级) 和晚年 (健康,生活方式,心理社会福祉),性别,个性和APOE e4状态的影响.
主要成果:
- 更高的认知功能,更好的身体功能和更大的身体活动与较低的死亡风险有关.
- 女性性别和非吸烟者地位也为更长寿做出了贡献.
- 早期和中年因素 (智商,教育,社会阶级),人格特征 (情绪稳定,良心),以及女性性别通过成人健康间接影响了生存.
结论:
- 了解长寿需要考虑整个生命过程中的因素.
- 人口,心理和健康变量对于解释极端长寿至关重要.
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